Steviol glycosides are currently being used as natural sweeteners by the food industry and Stevia rebaudiana has long been used as a sweet plant in South America for patients suffering from diabetes. In this study, a Stevia rebaudiana ethanolic extract (SREE) was prepared, analysed and tested for antioxidant activity in terms of free radical scavenging properties and antiproliferative effects in cervix (HeLa), pancreatic (MiaPaCa-2) and colonic (HCT116) cancer cells. The antiproliferative mechanism was confirmed by testing the effects on cyclin D1-CDK4. #Stevia#kombucha#ikombucha_ro#ikombucha https://pubmed.ncbi.nlm.nih.gov/27071804/
Hydroponics offers a viable solution for obtaining plant products that are rich in micronutrients and ultramicronutrients, such as selenium. Selenium plays a crucial role in strengthening the body's immune defense and acts as a potent antioxidant. Low levels of selenium have been associated with an increased risk of heart attacks, strokes, and cancer. Stevia rebaudiana Bertoni (SrB), a relatively new crop in plant cultivation, was the focus of the present study. SrB has numerous medicinal and prophylactic properties, and its leaves are rich in macro- and microelements, vitamins, and diterpene glycosides. #Stevia#kombucha#ikombucha_ro#ikombucha https://pubmed.ncbi.nlm.nih.gov/37522778/
Stevia is unaffected by stomach acid, pancreatic enzymes and the process of digestion. It travels essentially “untouched” by the digestive process until it reaches the large intestine. There it “reacts” with the gut flora. It is then absorbed in the colon and travels to the liver. It is then bound to glucuronic acid via the glucuronidation pathway and eventually excreted through the urine. The glucuronidation pathway is a major liver pathway that detoxifies drugs, pollutants, estrogen, and steroids, etc. #Stevia#kombucha#ikombucha_ro#ikombucha https://www.portalsalud.com/cuales-son-los-peligros-de-la-stevia_13092860/
Bladder cancer (BC) is a global health issue that lacks effective treatment strategies. Growing evidence suggests that various natural products possess anti-tumour effects. This study aims to identify a novel agent that can be used in the treatment of BC.
Collectively, our data suggest that stevioside can be a potential agent for the treatment of BC. #Stevia#kombucha#ikombucha_ro#ikombucha https://pubmed.ncbi.nlm.nih.gov/35820501/
It looks like "youtube" is covered already, but any #scuttlebutt about that is appreciated. The knowledge about what's best or hot at any time is also federated 😕
Überwachung: Interpol baut Big-Data-System Insight für "vorhersagende Analysen"
Interpol entwickelt eine Plattform, um riesige Datenmengen aus mehreren Quellen wie Social Media in unterschiedlichen Formaten effizient verarbeiten zu können.
Systeme, um nur die "riesigen Datenmengen", die frei verfügbar sind, durchzusehen und zu bewerten, müssen erst noch entwickelt werden.
Aber dann uns versuchen einzureden, dass die anlasslose Überwachung unserer privaten Kommunikation dem Ziel der der Bekämpfung von <hier beliebigen Vorwand einfügen - sind wir noch bei Kindern oder schon wieder bei Terrorismus?> dient. Als wären die überhaupt in der Lage, die jetzt bereits zu Verfügung stehenden Daten adequat zu verarbeiten.
De la buée sur les vitres de la fenêtre dont nous n'avions pas fermé les volets. C'est la première fois depuis le printemps. Les nuits commencent à être fraîches, eh oui.
Inventaire.io https://inventaire.io/welcome - Manage your physical books or other items (board games perhaps) and keep track of who has what when lending or borrowing items. ActivityPub enabled.
Thedesk.top - A bit overwhelmingly full-featured alternative UI to Mastodon/Firefish/Misskey/*key forks. Some aspects may be very confusing but for some, the workflow and customization it provides are powerful.
Gustul ceaiului de kombucha diferă de la un producător la altul în funcție de metodele de preparare. Tocmai de aceea vă invităm să testați cele 8 sortimente iKombucha. După o experiență de peste 7 ani în producerea de kombucha, am adăugat la rețetele noastre stevia ca și îndulcitor, pentru ca produsul final să nu fie prea acru la gust pentru majoritatea clienților. Am dezvoltat 8 sortimente cu diferite arome, care să acopere înr-o anumită măsură gustul de ferment și să ofere gusturi plăcute. #Stevia#kombucha#ikombucha_ro#ikombucha https://healthfully.com/stevia-and-cancer-5918164.html
Stevioside is a diterpene glycoside found in the leaf of Stevia rebaudiana, a traditional oriental medicinal herb, which has been shown to have various biological and ethno-medicinal activities including antitumor activity. In this study, we investigated the effects of stevioside on the cytotoxicity, induction of apoptosis, and the putative pathways of its action in human breast cancer cells (MCF-7). For the analysis of apoptotic pathway, measurement of reactive oxygen species (ROS) and assessment of mitochondrial transmembrane potential (MTP) were achieved. We showed that stevioside was a potent inducer of apoptosis and it conveyed the apoptotic signal via intracellular ROS generation; thereby inducing change in MTP and induction of mitochondrial mediated apoptotic pathway. Taken together, our data indicated that stevioside induces the ROS-mediated mitochondrial permeability transition and results in the increased expression of apoptotic proteins such as Bax, Bcl-2 and Caspase-9. Effect of stevioside on stress-related transcription factors like NF-E2-related factor-2 opens up a new vista for further studies. This is the first report on the mechanism of the antibreast cancer (in vitro) activity of stevioside. #Stevia#kombucha#ikombucha_ro#ikombucha https://pubmed.ncbi.nlm.nih.gov/23061910/
A β-galactosidase from Kluyveromyces lactis was found to specifically catalyze hydrolysis of the glycosyl ester linkage of stevioside to yield steviolbioside, a rare sweetener that also exists in Stevia rebaudiana leaves. In a packed bed reactor, a reaction coupling separation was realized and a production yield of steviolbioside reached 90% in 6 h. The hydrolysis product steviolbioside presented higher cytoxicity on human normal cells (hepatocytes cell L02 and intestinal epithelial cell T84) than stevioside did. Comparing to the typical chemotherapy agent, 5-fluorouracil (5-FU), steviolbioside presents much lower cytotoxicity on all assayed human normal cells; it presented notable inhibition on human hepatocarcinoma cell Hep3B, human breast cancer cell MDA-MB-231 and human pancreatic cancer cell BxPC-3. The remarkable inhibition on MDA-MB-231 cells makes steviolbioside a potential remedy for human breast cancer, when steviolbioside is served as a natural sweetener. #Stevia#kombucha#ikombucha_ro#ikombucha https://pubmed.ncbi.nlm.nih.gov/26593477/
Regarding nutritional benefits, the available studies, while numerous, do not provide proof that the consumption of artificial sweeteners as sugar substitutes is beneficial in terms of weight management, blood glucose regulation in diabetic subjects or the incidence of type 2 diabetes. Regarding nutritional risks (incidence of type 2 diabetes, habituation to sweetness in adults, cancers, etc.), it is not possible based on the available data to establish a link between the occurrence of these risks and the consumption of artificial sweeteners. However, some studies underline the need to improve knowledge of the links between intense sweeteners consumption and certain risks. #Stevia#kombucha#ikombucha_ro#ikombucha https://pubmed.ncbi.nlm.nih.gov/26430511/
"Wohnungsbaugipfel": Bauministerin für Kurswechsel bei Energiesparvorschriften
Das Hin und Her über das Heizungsgesetz hat viele Bürger verschreckt. Vor dem "Wohnungsbaugipfel" am Montag gibt es nun Kritik an Energiesparstandards.
"Das Hin und Her über das Heizungsgesetz hat viele Bürger verschreckt."
Nein. Die von Medien verbreiteten Lügen und das von der FDP passend koordinierte scheinbare Hin und Her hat die Bürger verschreckt. Genau wie geplant. Denn das Ziel war immer schon, den Fortschritt auszubremsen, damit Unternehmen die Menschen noch so lang wie möglich auszunehmen können. Jeder Tag weiter in die Sackgasse minimiert die Verluste der darin tätigen Unternehmen auf Kosten der Bürger.
