admiralteal,

The study is very clearly talking about non-diabetic patients, too..

These are almost certainly people who want the weight loss primarily for aesthetic reasons rather than health ones, and may face these terrible health complications as a result. Makes it even worse, I think.

You're almost certainly better off somewhat "fat" than skinny by way of a drug like this. Especially given that "fat" is an entirely subjective measure and the "objective" measures like BMI overweight/obese are not based on points of any kind of phase change in health outcomes but are just somewhat arbitrary statistical variations. Dramatic interventions like these should be reserved for people that have dramatic need, at least until we have such an intervention safe enough and with few enough side-effects for over-the-counter sale.

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