mihair

mihair, 7 months ago to science

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mihair, 7 months ago to fediverse

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mihair, 7 months ago to science

Raw stevia herb may harm your kidneys, reproductive system, and cardiovascular system. It may also drop blood pressure too low or interact with medications that lower blood sugar.
Although stevia is considered safe for people with diabetes, brands that contain dextrose or maltodextrin should be treated with caution.
Dextrose is glucose, and maltodextrin is a starch. These ingredients add small amounts of carbs and calories. Sugar alcohols may also slightly tip the carb count.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.healthline.com/health/food-nutrition/stevia-side-effects

Certain chemicals in stevia, including stevioside and rebaudioside A, are likely safe when used as a food sweetener. Side effects might include bloating, nausea, dizziness, and numbness.
There isn't enough reliable information to know if whole stevia or stevia extracts are safe or what the side effects might be.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.verywellhealth.com/stevia-side-effects-6890614

Stevia (Stevia rebaudiana) is a bushy shrub native to northeast Paraguay, Brazil, and Argentina. It's best known as a natural sweetener.
Stevia contains chemicals that are 200-300 times sweeter than sucrose sugar.
People take stevia for obesity, high blood pressure, diabetes, and many other conditions, but there is no good scientific evidence to support these uses.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.webmd.com/vitamins/ai/ingredientmono-682/stevia

Using stevia can reduce calories in foods and drinks, but it may also have some adverse effects. Possible side effects include nausea, bloating, low blood pressure, and hormone disruption.
Stevia is a non-nutritive or zero-calorie sweetener made of steviol glycosides. These are compounds extracted and refined from the leaves of the Stevia rebaudiana plant.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.medicalnewstoday.com/articles/319837

Epidemiologic studies (studies of patterns, causes, and control of diseases in groups of people) have examined possible associations between intakes of artificial sweeteners and risks of several cancers in people. It is important to keep in mind that studies of this type cannot establish cause-and-effect relationships because factors other than artificial sweetener use may potentially explain observed associations. However, these studies can provide important insights that can then be investigated in additional studies that can give more definitive answers.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://healthfully.com/stevia-and-cancer-5918164.html

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mihair, 7 months ago to science

You might find packets of stevia on restaurant tables and store shelves. Stevia can also be found in many other products you eat. If you’re eating products marketed as low calorie, check the ingredients list to see what type of sweetener was used.
Currently, there’s no evidence linking stevia to cancer when used in normal amounts. Some research suggests it may even have some health benefits. A number of studies stress the need for more research into the potential benefits and risks of stevia.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://foodinsight.org/everything-you-need-to-know-about-stevia-sweeteners/

Stevia may interact with drugs intended to treat hypertension and diabetes.
In animal studies, stevia didn’t affect fertility or pregnancy outcomes, but research on humans is lacking. If you’re pregnant or breastfeeding, stevia glycoside products may be consumed in moderation. Steer clear of whole-leaf stevia and crude stevia extracts while pregnant or nursing.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.medicinenet.com/stevia/article.htm

Stevia made with Reb-A is safe to use in moderation during pregnancy. If you’re sensitive to sugar alcohols, choose a brand that doesn’t contain erythritol.
Whole-leaf stevia and crude stevia extract, including stevia you’ve grown at home, are not safe to use if you’re pregnant.
It may seem strange that a highly refined product is considered safer than a natural one. This is a common mystery with herbal products.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.britannica.com/plant/stevia-plant

Stevia, a zero-calorie sugar substitute, is recognized as safe by the Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). In vitro and in vivo studies showed that stevia has antiglycemic action and antioxidant effects in adipose tissue and the vascular wall, reduces blood pressure levels and hepatic steatosis, stabilizes the atherosclerotic plaque, and ameliorates liver and kidney damage. The metabolism of steviol glycosides is dependent upon gut microbiota, which breaks down glycosides into steviol that can be absorbed by the host. In this review, we elucidated the effects of stevia's consumption on the host's gut microbiota. #Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/35456796/

A 2019 study reported a possible link between nonnutritive sweeteners, including stevia, and disruption in beneficial intestinal flora. The same study also suggested nonnutritive sweeteners may induce glucose intolerance and metabolic disorders.
As with most nonnutritive sweeteners, a major downside is the taste. Stevia has a mild, licorice-like taste that’s slightly bitter. Some people enjoy it, but it’s a turn-off for others.
In some people, stevia products made with sugar alcohols may cause digestive problems, such as bloating and diarrhea.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.webmd.com/food-recipes/what-is-stevia

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mihair, 7 months ago to science

Stevia is considered a "natural non-caloric sweetener." Saccharin and sucralose are considered "non-nutritive sweeteners" (few or no calories). Aspartame is a "nutritive sweetener" (adds some calories but far less than sugar).
Aspartame comes with a warning to be used cautiously (or not at all) by people with a rare genetic disease (called phenylketonuria, or PKU) because they have trouble metabolizing it; that's not true for the other sweeteners. And all four vary on their level of sweetness and aftertaste, which is likely why people often prefer one over another.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.health.harvard.edu/blog/sweeteners-time-to-rethink-your-choices-2019022215967

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mihair, 7 months ago to science

With a low to no calorie sugar count, artificial sweeteners may seem like a treat for people with diabetes. But recent research indicates that artificial sweeteners may actually be counterintuitive, especially if you’re looking to manage or prevent diabetes.
In fact, the increased consumption of these sugar substitutes may correlate to the increase of obesity and diabetes cases.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.healthline.com/health/type-2-diabetes/diabetes-stevia#overview

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mihair, 7 months ago to science

Stevia is an ideal replacement for traditional sugar, especially if you have diabetes or a carbohydrate-controlled diet. That way, you can enjoy sweet foods without dealing with diabetic complications. Unlike normal sugar made of sucrose, stevia contains stevioside. It is a glycoside compound, not a carbohydrate. Table sugar is absorbed into the bloodstream. As stevioside breaks down, the glucose is absorbed in the colon by bacteria.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://facty.com/food/nutrition/10-surprising-benefits-and-risks-of-the-alternative-sweetener-stevia/?style=quick&utm_source=adwords&adid=267723668343&ad_group_id=57749014289&utm_medium=c-search&utm_term=stevia&utm_campaign=FH-USA-Search-Health-Benefits-and-Risks-of-Stevia&gclid=EAIaIQobChMI1v_2gJqCgQMV1gQGAB1JAgLjEAAYAyAAEgL1VvD_BwE

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mihair, 7 months ago to science

Pancreatic cancer has an extremely poor prognosis, largely due to a poor record for early detection. Known risk factors for pancreatic cancer include obesity, diet, and diabetes, implicating glucose consumption and regulation as a key player. The role of artificial sweeteners may therefore be pertinent to disease kinetics. The oncogenic impact of artificial sweeteners is a highly controversial area. #Stevia #kombucha #ikombucha_ro #ikombucha
https://www.frontiersin.org/articles/10.3389/fonc.2017.00018/full

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mihair, 7 months ago to science

Stevia, a zero-calorie sugar substitute, is recognized as safe by the Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). In vitro and in vivo studies showed that stevia has antiglycemic action and antioxidant effects in adipose tissue and the vascular wall, reduces blood pressure levels and hepatic steatosis, stabilizes the atherosclerotic plaque, and ameliorates liver and kidney damage. The metabolism of steviol glycosides is dependent upon gut microbiota, which breaks down glycosides into steviol that can be absorbed by the host. In this review, we elucidated the effects of stevia’s consumption on the host’s gut microbiota. #Stevia #kombucha #ikombucha_ro #ikombucha
https://www.mdpi.com/2076-2607/10/4/744/htm

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mihair, 7 months ago to science

To help offset potential stevia induced gut challenges, support your gut flora with fiber and prebiotics like FOS10 (fructo-oligosaccharides). Increase your intake of beneficial bacteria Lactobacillus and Bifidus to aid in a healthier gut microbiome.
Consider foods and nutrients like cruciferous vegetables (Brussels sprouts, cabbage, broccoli, cauliflower, kale), silymarin, dandelion, resveratrol, curcumin, magnesium, zinc, limonene, B vitamins, and omega-3 oils to help your liver’s glucuronidation pathway.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.bbc.com/mundo/noticias/2013/07/130717_salud_nutricion_stevia_finde_gtg

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mihair, 7 months ago to science

Ancestral intake of the raw stevia leaf was extremely limited compared to current exposures of refined stevia found in many manufactured food products. I am a proponent of using foods in their natural, whole form when possible.
Avoid processed refined sugars and foods with added sugars, but rather use raw local honey, blackstrap molasses, real maple syrup, or other natural sugars. Think about it, would your grandmother or great grandmother use something like refined stevia in their made from scratch homemade recipes?
#Stevia #kombucha #ikombucha_ro #ikombucha
https://medlineplus.gov/spanish/druginfo/natural/682.html

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mihair, 7 months ago to science

Artificial sweeteners or intense sweeteners are sugar substitutes that are used as an alternative to table sugar. They are many times sweeter than natural sugar and as they contain no calories, they may be used to control weight and obesity. Extensive scientific research has demonstrated the safety of the six low-calorie sweeteners currently approved for use in foods in the U.S. and Europe (stevia, acesulfame-K, aspartame, neotame, saccharin and sucralose), if taken in acceptable quantities daily. There is some ongoing debate over whether artificial sweetener usage poses a health threat .This review article aims to cover thehealth benefits, and risks, of consuming artificial sweeteners, and discusses natural sweeteners which can be used as alternatives.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/25842566/

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mihair, 7 months ago to science

Stevia rebaudiana Bertoni is a perennial shrub with zero calorie content that has been increasing in popularity for its potential use as an adjuvant in the treatment of obesity. The level of evidence supporting general benefits to human health is insufficient. We conducted a review of the literature summarizing the current knowledge and role in human disease.
A growing body of evidence indicates that Stevia rebaudiana Bertoni is protective against malignant conversion by inhibition of DNA replication in human cancer cell growth in vitro.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/29995279/

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mihair, 7 months ago to science

Gustul ceaiului de kombucha diferă de la un producător la altul în funcție de metodele de preparare. Tocmai de aceea vă invităm să testați cele 8 sortimente iKombucha. După o experiență de peste 7 ani în producerea de kombucha, am adăugat la rețetele noastre stevia ca și îndulcitor, pentru ca produsul final să nu fie prea acru la gust pentru majoritatea clienților. Am dezvoltat 8 sortimente cu diferite arome, care să acopere înr-o anumită măsură gustul de ferment și să ofere gusturi plăcute.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://healthfully.com/stevia-and-cancer-5918164.html

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mihair, 7 months ago to science

Stevioside is a diterpene glycoside found in the leaf of Stevia rebaudiana, a traditional oriental medicinal herb, which has been shown to have various biological and ethno-medicinal activities including antitumor activity. In this study, we investigated the effects of stevioside on the cytotoxicity, induction of apoptosis, and the putative pathways of its action in human breast cancer cells (MCF-7). For the analysis of apoptotic pathway, measurement of reactive oxygen species (ROS) and assessment of mitochondrial transmembrane potential (MTP) were achieved. We showed that stevioside was a potent inducer of apoptosis and it conveyed the apoptotic signal via intracellular ROS generation; thereby inducing change in MTP and induction of mitochondrial mediated apoptotic pathway. Taken together, our data indicated that stevioside induces the ROS-mediated mitochondrial permeability transition and results in the increased expression of apoptotic proteins such as Bax, Bcl-2 and Caspase-9. Effect of stevioside on stress-related transcription factors like NF-E2-related factor-2 opens up a new vista for further studies. This is the first report on the mechanism of the antibreast cancer (in vitro) activity of stevioside.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/23061910/

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mihair, 7 months ago to science

A β-galactosidase from Kluyveromyces lactis was found to specifically catalyze hydrolysis of the glycosyl ester linkage of stevioside to yield steviolbioside, a rare sweetener that also exists in Stevia rebaudiana leaves. In a packed bed reactor, a reaction coupling separation was realized and a production yield of steviolbioside reached 90% in 6 h. The hydrolysis product steviolbioside presented higher cytoxicity on human normal cells (hepatocytes cell L02 and intestinal epithelial cell T84) than stevioside did. Comparing to the typical chemotherapy agent, 5-fluorouracil (5-FU), steviolbioside presents much lower cytotoxicity on all assayed human normal cells; it presented notable inhibition on human hepatocarcinoma cell Hep3B, human breast cancer cell MDA-MB-231 and human pancreatic cancer cell BxPC-3. The remarkable inhibition on MDA-MB-231 cells makes steviolbioside a potential remedy for human breast cancer, when steviolbioside is served as a natural sweetener.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/26593477/

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mihair, 7 months ago to science

Regarding nutritional benefits, the available studies, while numerous, do not provide proof that the consumption of artificial sweeteners as sugar substitutes is beneficial in terms of weight management, blood glucose regulation in diabetic subjects or the incidence of type 2 diabetes. Regarding nutritional risks (incidence of type 2 diabetes, habituation to sweetness in adults, cancers, etc.), it is not possible based on the available data to establish a link between the occurrence of these risks and the consumption of artificial sweeteners. However, some studies underline the need to improve knowledge of the links between intense sweeteners consumption and certain risks.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/26430511/

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mihair, 7 months ago to science

The essential oil extracted by hydrodistillation from the flowering twigs of Stevia rebaudiana Bertoni (Asteraceae) was fractioned by chromatography. Forty-three constituents were characterized with the help of GC, GC-MS and other spectroscopic techniques. The essential oil was found to be a complex mixture of mono- and sesqui-terpenes. The cytotoxicity of the essential oil and its fractions was evaluated by sulforhodamine B (SRB) based assay against two cancer cell types viz. C-6 (rat glioma cells) and CHOK1 (Chinese hamster ovary cells). The essential oil and its fractions showed promising cytotoxicity against both cell lines. The highest activity (95.6+/-0.6%) was show by the essential oil on the C-6 cell line at a concentration of 400 microg/mL, which was comparable with that of the standard drug vinblastin.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/25026731/

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mihair, 7 months ago to science

Stevia, a zero-calorie sugar substitute, is recognized as safe by the Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). In vitro and in vivo studies showed that stevia has antiglycemic action and antioxidant effects in adipose tissue and the vascular wall, reduces blood pressure levels and hepatic steatosis, stabilizes the atherosclerotic plaque, and ameliorates liver and kidney damage. The metabolism of steviol glycosides is dependent upon gut microbiota, which breaks down glycosides into steviol that can be absorbed by the host. In this review, we elucidated the effects of stevia's consumption on the host's gut microbiota. Due to the lack of randomized clinical trials in humans, we included in vitro using certain microbial strains and in vivo in laboratory animal studies. Results indicated that stevia consumption has a potential benefit on the microbiome's alpha diversity. Alterations in the colonic microenvironment may depend on the amount and frequency of stevia intake, as well as on the simultaneous consumption of other dietary components. The anti-inflammatory properties of stevioside were confirmed in vitro by decreasing TNF-α, IL-1β, IL-6 synthesis and inhibiting of NF-κB transcription factor, and in vivo by inhibiting NF-κB and MAPK in laboratory animals.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/35456796/

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mihair, 7 months ago to science

Steviol glycosides (SGs) in Stevia (Stevia rebaudiana Bertoni) leaves are important due to their high sweetness and low calorific value. The yield of SGs is dependent on fertilization regimes, but the relationship between nitrogen (N) administration and SGs synthesis is still unclear. In this study, we investigate the effects of N rates on SGs production through hydroponic and plot experiments. The SGs yield was not significantly changed by N fertilization, but leaf SGs concentrations were significantly reduced due to the "dilution effect". Additionally, N addition decreased leaf carbon (C)/N ratio and soluble sugar concentration, accompanied with the inhibited phosphoenolpyruvate carboxylase and L-phenylalanine ammonia_lyase activities. A significant positive correlation between leaf SGs concentrations, C/N ratio and soluble sugar concentration was observed. Overall, we suggest that N-driven Stevia growth negatively affects SGs concentrations. The leaf C/N ratio and soluble sugar changes indicated the occurrence of metabolic reprogramming.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/31195254/

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mihair, 7 months ago to science

Plant growth and secondary metabolism are commonly regulated by external cues such as light, temperature and water availability. In this study, the influences of low and high temperatures, dehydration, photoperiods, and different growing stages on the changes of steviol glycosides (SGs) contents and transcription levels of fifteen genes involved in SGs biosynthesis of Stevia rebaudiana Bertoni were examined using HPLC and RT-PCR. The observations showed that the transcript levels of all the fifteen genes were maximum under 25 °C treatment, and the transcription of SrDXS, SrDXR, SrMCT, SrCMK, SrMDS, SrHDS, SrHDR, SrIDI, SrGGDPS, SrCPPS1, SrUGT85C2 and SrUGT76G1 were restrained both in low temperature (15 °C) and high temperature (35 °C). Most genes in SGs biosynthesis pathway exhibited down-regulation in dehydration. To elucidate the effect of photoperiods, the plants were treated by different simulated photoperiods (8 L/16 D, 1 0L/14 D, 14 L/10 D and 16 L/8 D), but no significant transcription changes were observed. In the study of growing stages, there were evident changes of SGs contents, and the transcript levels of all the fifteen genes were minimal in fast growing period, and exhibited evident increase both in flower-bud appearing stage and flowering stage. The obtained results strongly suggest that the effect of environmental cues on steviol glycosides contents and transcription of corresponding biosynthetic genes in S. rebaudiana is significant. It is worth to study deeply.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/25500454/

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